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Novel Percutaneous Approach for Deployment of 3D Printed Coronary Stenosis Implants in Swine Models of Ischemic Heart Disease
Published on: February 18, 2020
[Multislice computed tomoangiography in assessment of coronary stent lumen]
Insights
Drug-eluting stents reduce in-stent restenosis, but Multi-Slice computed Coronary Angiography (CT-CA) requires further technological advancements for effective follow-up imaging of coronary stents.
Area of Science:
- Cardiology
- Medical Imaging
- Interventional Cardiology
Background:
- Coronary artery stenosis treatment evolved from bypass surgery to stenting.
- Drug-eluting stents have decreased in-stent restenosis (ISR) rates.
- Recurrent symptoms necessitate imaging follow-up for stented patients.
Purpose of the Study:
- To evaluate the role of Multi-Slice computed Coronary Angiography (CT-CA) in follow-up of coronary stents.
- To identify factors affecting in-stent lumen depiction by CT-CA.
- To assess the clinical applicability of CT-CA for stented coronary arteries.
Main Methods:
- Review of current CT-CA technology and its limitations for stent evaluation.
- Analysis of technical performance requirements for CT scanners.
- Consideration of operator experience in CT-CA interpretation.
Main Results:
- CT-CA is under evaluation for coronary stent follow-up.
- Several factors can impede accurate in-stent lumen visualization.
- CT-CA may be clinically useful in select patient groups.
- High technical and training standards are currently demanded.
Conclusions:
- CT-CA shows potential for evaluating coronary stents but faces technical challenges.
- Improvements in CT technology (contrast, resolution) are needed for clinical implementation.
- Further research and technological advancements are crucial for widespread CT-CA use in stented coronary artery follow-up.
Abstract:
The treatment of coronary artery stenosis has progressively shifted over the past decades from surgical (bypasses) to percutaneous (stenting). Recent introduction of drug-eluting stents further reduced the occurrence of in-stent re-stenosis (ISR). However a non-negligible number of patients need imaging tests when symptoms recur Multi-Slice computed Coronary Angiography (CT-CA) is a clinical reality for evaluation of coronary artery stenosis, but still under evaluation in the follow-up of coronary stents. Several factors may impair proper depiction of in-stent lumen even with the most recent CT equipments. In highly selected populations CT-CA may play a clinical role even though the performance requirements both from the technical standpoint (i.e., CT scanner) and from the training (i.e., operators'experience) are still very demanding. In the meantime CT technology should improve towards higher contrast, spatial and temporal resolution in order to achieve the results that may be proper for clinical implementation.
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