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Updated: May 20, 2026

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
Published on: September 27, 2024
Current trends in the chemotherapy of colorectal cancer
M A Berciano-Guerrero1, J C Villa-Guzmán, R Acosta-Guerrero
1Department of Clinical Oncology, General University Hospital of Ciudad Real (HGUCR), Ciudad Real, Spain. migueberci@gmail.com
Abstract:
The increase in the therapeutic arsenal in the last 20 years, has given rise to changes in treating colorectal cancer (CRC) with only pyrimidines to combine several cytotoxic drugs. However, the present question is to determine the optimal sequence of this combination. This review presents an update of data on chemical and clinical features of chemotherapy used for colorectal cancer and the mechanisms of cellular resistance and potential predictive and prognostic biomarkers, which may contribute to a better selection of a therapeutic strategy.
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