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Updated: May 20, 2026

Comprehensive Evaluation of the Effectiveness and Safety of Placenta-Targeted Drug Delivery Using Three Complementary Methods
09:04

Comprehensive Evaluation of the Effectiveness and Safety of Placenta-Targeted Drug Delivery Using Three Complementary Methods

Published on: September 10, 2018

Cefazolin plasma protein binding and its covariates in neonates

A Smits1, A Kulo, R Verbesselt

  • 1Neonatal Intensive Care Unit, University Hospitals Leuven, Herestraat 49, 3000, Leuven, Belgium. anne.smits@uzleuven.be

European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology
|July 27, 2012
PubMed
Summary

Neonatal cefazolin (CFZ) protein binding is higher than in adults and varies with albumin levels, bilirubin, and postmenstrual age (PMA). Understanding this binding is crucial for optimizing CFZ dosing in newborns.

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