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Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
Maternal depressive symptoms and the risk of overweight in their children
Liang Wang1, James L Anderson, William T Dalton Iii
1Department of Biostatistics and Epidemiology, College of Public Health, East Tennessee State University, PO Box 70259, Johnson City, TN 37614, USA. DrLiangWang@gmail.com
Insights
Persistent maternal depression symptoms in early childhood are linked to a higher risk of childhood overweight. Children of mothers with persistent depression showed a 2.13 times increased likelihood of being overweight.
Area of Science:
- Pediatrics
- Child Psychology
- Public Health
Background:
- Maternal mental health significantly influences child development.
- Childhood obesity is a growing public health concern with long-term implications.
Purpose of the Study:
- To investigate the association between maternal depressive symptoms in early childhood and offspring overweight.
- To determine if persistent maternal depression increases the risk of childhood obesity.
Main Methods:
- Longitudinal study using data from 1,090 children (grades 1, 3, 6).
- Maternal depressive symptoms assessed using the Center for Epidemiologic Studies Depression Scale (CES-D) at child ages 1, 24, and 36 months.
- Childhood overweight defined by CDC BMI percentiles; analyzed using generalized estimating equations.
Main Results:
- Children of mothers with persistent depressive symptoms (at all 3 time points) were 1.695 times more likely to be overweight (adjusted for child characteristics).
- This risk increased to 2.13 times more likely when further adjusted for maternal characteristics.
- A dose-response relationship may exist, with persistent symptoms posing a greater risk.
Conclusions:
- Persistent maternal depressive symptoms are associated with an increased risk of childhood overweight.
- Early identification and intervention for maternal depression may aid in childhood obesity prevention.
- Children of mothers experiencing persistent depression warrant targeted obesity prevention strategies.
Abstract:
To examine the association between maternal depressive symptoms during early childhood of their offspring and later overweight in the children. Only children (n = 1,090) whose weights and heights were measured at least once for three time points (grades one, three and six) from the National Institute of Child Health and Human Development Study were included. Maternal depressive symptoms, defined as a Center for Epidemiologic Studies Depression Scale (CES-D) score of 16 or greater, were assessed using CES-D when the child was 1, 24, and 36 months. Childhood overweight was based on standardized height and weight measures taken during the interviews, and was defined according to appropriate CDC age- and sex-specific BMI percentiles. Generalized estimating equation was used to examine the impact of maternal depressive symptoms on the childhood overweight after adjusting for covariates. Compared to children of mothers without depression at any of the three time points, when children were one, 24 and 36 months of age, children of mothers with depression at all three time points were 1.695 times more likely to be overweight after adjusting for other child characteristics (95 % CI = 1.001-2.869). When further adjusted for maternal characteristics, children of mothers with depression at all three time points were 2.13 times more likely to be overweight (95 % CI = 1.05-4.31). Persistent maternal depressive symptoms may be associated with an increased risk of childhood overweight in their offspring. Children of mothers with depression may benefit from special attention in terms of obesity prevention.
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