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Updated: May 20, 2026

Normothermic Negative Pressure Ventilation Ex Situ Lung Perfusion: Evaluation of Lung Function and Metabolism
Published on: February 14, 2022
[Application of artificial lung respiration in intensive care units in Russia: national epidemiological research
Unlabelled:
The purpose of the research is to study the real use of the various modes and parameters of prolonged respiratory support in Russia.
Materials And Methods:
The study included all patients from ICU with no limitation by sex and age with ALV duration more than 12 hours in the period from February 7 to 11. 2011. 470 patients, including 104 children under the age of 15 years, from 101 ICU in Russian Federation, 2 ICU in the Republic of Belarus and 1 ICU in Ukraine (total 104 centres). The collection of information performed through online forms.
Results:
Total lethality was 35.1% (139 from 396 patients), in case of the ARDS development - 44.9%. The frequency of ARDS development - 18.7%. According to the study "Ru Vent" doctors mostly prefer managed modes of respiratory support (SIMV 45.1%, A/C 20.2%, BiPAP 12.6%) which can partly be explained by a large proportion ofpatients with Central nervous system pathology, included in the study (39.8%). Frequency of non-invasive respiratory support use amounted to 1.1%. Real respiratory volume based on ideal body weight calculation, averaged for men 8.13 (6.84-9.33) ml/kg, for women - 9.1 (7.6-10.9) ml/kg, which is above the "ideal" respiratory volume 6 ml/kg in 1.35 times (1.14-1.56) for men (n=251) and in 1.51 times (1.27 - 1.81) for women (r=161). PEEP median amounted to 5 mbar, in case ofARDS development - 6 mbar.
Conclusion:
The results of the Russian national epidemiological research of ALV use in ICU ("RuVent) showed comparable data with real international clinical practice. The used tidal volumes are slightly overestated, and the values ofthe PEEP are understated in comparison with the national and international recommendations.
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