[Primary and secondary perosteal reactions (author's transl)]

Radiological and histological comparative analysis of the morphological changes of periosteal reaction. A distinction is made between secondary periosteal reaction (so called periostitis ossificans or osseous periostosis), primary periosteal lesions (due to inflammation, trauma, fibrosis and neoplasia) and soft tissue lesions involving the adjacent periosteum. Secondary periosteal reactions are most frequent, indicating the need for search of its cause. Here biopsy of the periosteal reaction is often important for establishing an early diagnosis.