Related Experiment Video

Updated: May 20, 2026

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
07:56

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts

Published on: January 29, 2018

Human biology at the interface of paediatrics: measuring bone mineral accretion during childhood

Babette S Zemel1

  • 1Division of Gastroenterology, Hepatology and Nutrition, The Children's Hospital of Philadelphia, The Perelman School of Medicine, University of Pennsylvania, 3535 Market Street, room 1560, Philadelphia, PA 19104-4399, USA. zemel@email.chop.edu

Annals of Human Biology
|July 28, 2012
PubMed

Insights

Paediatric bone health assessment applies Tanner

Area of Science:

  • Pediatric bone health assessment
  • Human biology and pediatrics collaboration

Background:

  • Tanner's paradigm emphasizes precise growth measurements and variability.
  • Paediatric bone health assessment aligns with this paradigm.
  • It involves collaboration between human biologists and pediatricians.

Purpose of the Study:

  • To review the clinical assessment of bone density in children.
  • To discuss technological advancements in pediatric bone health assessment.
  • To explore factors influencing pediatric bone health outcomes.

Main Methods:

  • Review of clinical assessment reasons and technological developments.
  • Analysis of reference curve development.
  • Examination of growth, body composition, pubertal timing, genetics, and lifestyle effects.

Main Results:

  • Clinical assessment of pediatric bone density is crucial.
  • Technological advancements have improved assessment accuracy.
  • Growth, body composition, pubertal timing, genetics, and lifestyle significantly impact bone health.

Conclusions:

  • Paediatric bone health assessment is a vital, evolving field.
  • Understanding influencing factors is key to optimizing skeletal growth.
  • Collaboration enhances our knowledge of children's skeletal development.
Abstract

More Related Videos

Culturing and Measuring Fetal and Newborn Murine Long Bones06:58

Culturing and Measuring Fetal and Newborn Murine Long Bones

Published on: April 26, 2019

Assessment of Child Anthropometry in a Large Epidemiologic Study09:36

Assessment of Child Anthropometry in a Large Epidemiologic Study

Published on: February 2, 2017

Related Concept Videos

Changes in the Appendicular Skeleton with Age01:09

Changes in the Appendicular Skeleton with Age

The upper and lower limb initially develops as a small bulge called a limb bud, which appears on the lateral side of the early embryo. The upper limb bud appears near the end of the fourth week of development, with the lower limb bud appearing shortly after.
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
Hormones and Bone Tissue01:17

Hormones and Bone Tissue

The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
Bone Disorders01:29

Bone Disorders

Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone Formation by Intramembranous Ossification01:29

Bone Formation by Intramembranous Ossification

Intramembranous ossification is one of the two processes involved in the development of bones within an embryo. The flat bones of the face, most of the cranial bones, and the clavicles are formed via this process. During intramembranous ossification, the bones develop directly from sheets of undifferentiated mesenchymal connective tissue.
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into...
Bone Remodeling01:40

Bone Remodeling

Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...