Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Negative and Cognitive Symptoms of Schizophrenia01:30

Negative and Cognitive Symptoms of Schizophrenia

Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
Antisocial Personality Disorder01:24

Antisocial Personality Disorder

Antisocial personality disorder is a chronic mental health condition characterized by persistent patterns of disregard for the rights and well-being of others. Individuals with antisocial personality disorder exhibit behaviors that include deceitfulness, impulsivity, irresponsibility, aggression, and a profound lack of empathy. These traits often manifest early in life and persist into adulthood, leading to significant personal, social, and legal consequences.
Behavioral Characteristics and...
Drug Dependence01:17

Drug Dependence

Medications are typically administered to achieve therapeutic effects. Some drugs can modify an individual's mood and perception, frequently resulting in various enjoyable experiences. However, this can result in drug dependency, a condition marked by continuous drug use despite potential negative consequences. Drug dependency primarily falls into two categories: psychological and physical dependence. Psychological dependence occurs when the pleasurable feelings induced by the drug...
Classification of Illness01:17

Classification of Illness

The meaning of illness is individualized to each person who experiences an alteration in health. In contrast, disease is a medical term indicating a pathological change in the structure and function of the body or mind. It is a condition that has specific symptoms and boundaries.
An illness is a response to a disease in which the person's level of functioning is changed compared with a previous level. The general classification of illness includes acute and chronic.
Acute illness is severe and...
CNS Depressants: Alcohol and Nicotine01:27

CNS Depressants: Alcohol and Nicotine

Ethanol, a clear colorless alcohol, has been consumed by humans for millennia, but its effects on the body are far from benign. At lower doses, it induces decreased inhibitions and loquaciousness, leading to its social appeal. However, it can cause severe consequences at higher doses, such as coma and respiratory depression, due to its zero-order elimination kinetics. Chronic ethanol abuse wreaks havoc on multiple organ systems, particularly the CNS and the liver. Abrupt cessation of ethanol...
Substance Use Disorders Affecting Sleep01:24

Substance Use Disorders Affecting Sleep

Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Using Iterative Experimentation to Accelerate Program Improvement: A Case Example.

Evaluation review·2020
Same author

Magnetic Resonance Spectroscopy of the Brain in Alcohol Abuse.

Alcohol health and research world·2019
Same author

Borderline personality disorder symptoms in treatment-naïve actively drinking alcoholics.

Alcohol (Fayetteville, N.Y.)·2018
Same author

EEG coherence related to fMRI resting state synchrony in long-term abstinent alcoholics.

NeuroImage. Clinical·2017
Same author

P3b amplitude is not reduced in abstinent alcoholics with a current MDD.

Alcohol (Fayetteville, N.Y.)·2017
Same author

Resting state synchrony in long-term abstinent alcoholics: Effects of a current major depressive disorder diagnosis.

Alcohol (Fayetteville, N.Y.)·2017
Same journal

COVID-19 pandemic-related changes in utilization of telehealth and treatment overall for alcohol use problems.

Alcoholism, clinical and experimental research·2022
Same journal

The relationship between fathers' heavy episodic drinking and fathering involvement in five Asia-Pacific countries: An individual participant data meta-analysis.

Alcoholism, clinical and experimental research·2022
Same journal

Screening for hazardous alcohol use in the Emergency Department: Comparison of phosphatidylethanol with the Alcohol Use Disorders Identification Test and the Timeline Follow-back.

Alcoholism, clinical and experimental research·2022
Same journal

Combination treatment with varenicline and naltrexone reduces World Health Organization risk drinking levels.

Alcoholism, clinical and experimental research·2022
Same journal

College students' virtual and in-person drinking contexts during the COVID-19 pandemic.

Alcoholism, clinical and experimental research·2022
Same journal

Does state repeal of alcohol exclusion laws increase problem drinking?

Alcoholism, clinical and experimental research·2022
See all related articles

Related Experiment Video

Updated: May 20, 2026

A Procedure to Study Stress-Induced Relapse of Heroin Seeking after Punishment-Imposed Abstinence
08:05

A Procedure to Study Stress-Induced Relapse of Heroin Seeking after Punishment-Imposed Abstinence

Published on: March 23, 2022

Antisocial symptoms decrease to normal levels in long-term abstinence.

George Fein1, David Fein

  • 1Neurobehavioral Research, Inc, Honolulu, Hawaii 96814, USA. george@nbresearch.com

Alcoholism, Clinical and Experimental Research
|July 28, 2012
PubMed
Summary
This summary is machine-generated.

Antisocial behavior decreases with long-term abstinence from substance dependence, even though tendencies toward social deviance persist. Executive control may inhibit these underlying antisocial dispositions.

More Related Videos

Social Threat-Safety Test Uncovers Psychosocial Stress-Related Phenotypes
05:03

Social Threat-Safety Test Uncovers Psychosocial Stress-Related Phenotypes

Published on: December 15, 2023

A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers
08:05

A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers

Published on: January 5, 2018

Related Experiment Videos

Last Updated: May 20, 2026

A Procedure to Study Stress-Induced Relapse of Heroin Seeking after Punishment-Imposed Abstinence
08:05

A Procedure to Study Stress-Induced Relapse of Heroin Seeking after Punishment-Imposed Abstinence

Published on: March 23, 2022

Social Threat-Safety Test Uncovers Psychosocial Stress-Related Phenotypes
05:03

Social Threat-Safety Test Uncovers Psychosocial Stress-Related Phenotypes

Published on: December 15, 2023

A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers
08:05

A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers

Published on: January 5, 2018

Area of Science:

  • Neuroscience
  • Psychiatry
  • Addiction Research

Background:

  • Previous studies indicated elevated antisocial symptoms and disposition in long-term abstinent individuals with alcohol dependence compared to controls.
  • While current antisocial symptoms decreased to subdiagnostic levels in long-term abstinence, their precise quantification was limited.

Purpose of the Study:

  • To measure social deviance proneness, antisocial disposition, and lifetime/current antisocial symptoms in individuals with varying abstinence durations.
  • To compare these measures between substance-dependent individuals (short- and long-term abstinence) and non-substance-abusing controls (NSAC).

Main Methods:

  • Assessment of social deviance proneness, antisocial disposition, and lifetime/current antisocial symptoms.
  • Inclusion of short-term abstinent, long-term abstinent, and NSAC groups.

Main Results:

  • Lifetime antisocial symptoms, social deviance proneness, and antisocial disposition were significantly elevated in both short- and long-term abstinent groups.
  • Current antisocial symptoms were markedly reduced in long-term versus short-term abstinent individuals, approaching control levels.
  • Social deviance proneness and antisocial disposition remained elevated in long-term abstinence.

Conclusions:

  • Antisocial behavior diminishes with extended abstinence from substance dependence.
  • Elevated social deviance proneness and antisocial disposition persist despite behavioral improvements.
  • A top-down model is proposed, suggesting executive control inhibits deviance-prone tendencies during long-term abstinence.