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Low ankle-brachial index is an independent predictor of poor functional outcome in acute cerebral infarction

Jinkwon Kim1, Dong Hyun Lee, Myoung-Jin Cha

  • 1Department of Neurology, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemoon-ku, 120-752 Seoul, Republic of Korea.

Atherosclerosis
|July 28, 2012
PubMed

Insights

Low ankle-brachial blood pressure index (ABI) in acute cerebral infarction patients indicates a higher risk of poor long-term functional outcome. Screening for low ABI may identify at-risk individuals for improved treatment.

Area of Science:

  • Neurology
  • Cardiovascular Medicine
  • Diagnostic Medicine

Background:

  • The ankle-brachial blood pressure index (ABI) is a key diagnostic tool for peripheral arterial disease and systemic atherosclerosis.
  • Acute cerebral infarction (stroke) poses significant risks for long-term patient functional status.

Purpose of the Study:

  • To determine if a low ABI is linked to long-term functional outcomes in patients who have experienced an acute cerebral infarction.
  • To assess the prognostic value of ABI in stroke survivors.

Main Methods:

  • A cohort of 775 patients with acute cerebral infarction underwent ABI measurement during admission.
  • Poor functional outcome was defined as a modified Rankin Scale score > 2 at three months post-stroke.
  • Logistic regression analysis was employed to examine the association between low ABI and functional outcome, adjusting for covariates.

Main Results:

  • A low ABI (<0.9) was identified in 10.1% of the study population.
  • 16.9% of patients experienced poor functional outcome at three months.
  • After adjusting for cardiovascular risk factors and cerebral atherosclerosis, a low ABI independently predicted poor functional outcome (OR 2.523, p=0.005).

Conclusions:

  • A low ABI is significantly associated with an increased risk of poor functional outcome following acute cerebral infarction.
  • Routine ABI screening in stroke patients could identify individuals requiring closer monitoring and intervention.
  • Tailored management strategies for patients with low ABI may enhance long-term recovery and functional status.
Abstract

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