Related Experiment Video
Updated: May 20, 2026
Intra-Cardiac Injection of Human Prostate Cancer Cells to Create a Bone Metastasis Xenograft Mouse Model
Published on: November 4, 2022
[Metabolic and osteogenic pattern of prostate cancer bone metastases]
1Unidad PET/TC, CETIR-ERESA, Esplugues de Llobregat, Barcelona, España. jrgarcia@cetir.es
Abstract:
The current protocols include the bone scintigraphy and choline PET/CT to localize recurrence in patients having elevated serum PSA after treatment for prostate cancer. Both methods show good agreement in the diagnosis of bone metastases, however conflicting results can be found. We present three cases in which a PET/CT was performed with (18)F-Fluoride due to disagreement between the bone scintigraphy and (11)C-Choline PET/CT. The (18)F-Fluoride PET/CT was capable of confirming the existence of bone metastasis in all of them, so it may be an alternative to the MRI as a tracer of second bone imaging modality, although its use is limited by cost and availability.
