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Updated: May 20, 2026

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
Published on: May 26, 2023
Perforated mitral valve annular phlegmon with ventriculo-atrial fistula
Corina E O'Dowd1, Bruce Garlick, Paul Bartley
1University of Queensland, Australia.
Abstract:
Herein we describe a case of perforated mitral valve annular abscess/phlegmon that presented as a new pan-systolic murmur in the setting of hallux osteomyelitis requiring amputation. We discuss the investigations, imaging and complex management challenges arising from this rare condition and the importance of considering a diagnosis of infective endocarditis in patients with a new cardiac murmur.
Insights
A perforated mitral valve annular abscess, a rare cardiac condition, can manifest as a new heart murmur. Prompt diagnosis and management are crucial for patients with osteomyelitis and new murmurs.
Area of Science:
- Cardiology
- Infectious Diseases
- Surgical Pathology
Background:
- Infective endocarditis is a serious infection of the heart valves.
- Mitral valve annular abscesses are rare but potentially life-threatening complications.
Observation:
- A patient with hallux osteomyelitis requiring amputation presented with a new pansystolic murmur.
- Investigations revealed a perforated mitral valve annular abscess/phlegmon.
Findings:
- The case highlights the diagnostic challenges and complex management of this rare condition.
- Imaging and clinical correlation were essential for accurate diagnosis.
Implications:
- Clinicians should consider infective endocarditis in patients with new cardiac murmurs, especially those with risk factors like osteomyelitis.
- Early recognition and multidisciplinary management are critical for improving patient outcomes.
Related Concept Videos
Mitral Stenosis I: Introduction
Mitral Valve Prolapse I: Introduction
Mitral Regurgitation I: Introduction
Mitral Stenosis III: Medical Management
Mitral Stenosis II: Clinical features and Diagnostic Tests
Mitral Valve Prolapse II: Assessment and Management
