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Magnetic resonance imaging in pantothenate kinase-2-associated neurodegeneration
Paramdeep Singh1, Kavita Saggar, Maneet Kaur
1Department of Radiodiagnosis, Dayanand Medical College and Hospital, Ludhiana, Punjab, India.
Abstract:
Pantothenate kinase-2-associated neurodegeneration (PKAN) is a rare autosomal recessive pediatric neurodegenerative disorder characterized by rigidity, dystonia, impaired postural reflexes, and progressive dementia. On T2-weighted magnetic resonance imaging images, marked low signal intensity is seen in the globus pallidus. This low signal intensity surrounds a central region of high signal intensity in the anteromedial globus pallidus, giving an eye-of-the-tiger appearance.

