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Functional divergence of gene duplicates - a domain-centric view

Mugdha Khaladkar1, Sridhar Hannenhalli

  • 1Department of Biology, University of Pennsylvania, Philadelphia, PA 19104, USA.

BMC Evolutionary Biology
|July 31, 2012
PubMed
Summary

Gene duplicates evolve asymmetrically, primarily due to differences within specific protein domains. This domain-level divergence in evolutionary rates correlates with distinct spatial gene expression patterns in teleost fishes.

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