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Antidiarrhoeal efficacy of Mangifera indica seed kernel on Swiss albino mice
S Rajan1, H Suganya, T Thirunalasundari
1Department of Microbiology, M. R. Govt Arts College, Mannargudi-614 001, Thiruvarur District, Tamilnadu, India.
Objective:
To examine the antidiarrhoeal activity of alcoholic and aqueous seed kernel extract of Mangifera indica (M. indica) on castor oil-induced diarrhoeal activity in Swiss albino mice.
Methods:
Mango seed kernels were processed and extracted using alcohol and water. Antidiarrhoeal activity of the extracts were assessed using intestinal motility and faecal score methods.
Results:
Aqueous and alcoholic extracts of M. indica significantly reduced intestinal motility and faecal score in Swiss albino mice.
Conclusions:
The present study shows the traditional claim on the use of M. indica seed kernel for treating diarrhoea in Southern parts of India.
