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Congenital hypothyroidism caused by excess prenatal maternal iodine ingestion

Kara J Connelly1, Bruce A Boston, Elizabeth N Pearce

  • 1Department of Pediatrics, Division of Pediatric Endocrinology, Oregon Health & Science University Doernbecher Children's Hospital, Portland, OR 972389, USA. connellk@ohsu.edu

The Journal of Pediatrics
|July 31, 2012
PubMed

We report the cases of 3 infants with congenital hypothyroidism detected with the use of our newborn screening program, with evidence supporting excess maternal iodine ingestion (12.5 mg/d) as the etiology. Levels of whole blood iodine extracted from their newborn screening specimens were 10 times above mean control levels. Excess iodine ingestion from nutritional supplements is often unrecognized.

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