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In Vivo Modeling of the Morbid Human Genome using Danio rerio
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Steroid 21-hydroxylase gene mutational spectrum in 50 Tunisian patients: characterization of three novel

Ilhem Ben Charfeddine1, Felix G Riepe, Eric Clauser

  • 1Laboratory of Human Cytogenetics, Molecular Genetics and Reproductive Biology, Farhat Hached University Hospital, Street Ibn El Jazzar, 4000 Sousse, Tunisia. ilhem_bc@yahoo.fr

Gene
|July 31, 2012
PubMed

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Mutations01:39

Mutations

Overview
Mutations01:35

Mutations

Mutations are changes in the sequence of DNA. These changes can occur spontaneously or they can be induced by exposure to environmental factors. Mutations can be characterized in a number of different ways: whether and how they alter the amino acid sequence of the protein, whether they occur over a small or large area of DNA, and whether they occur in somatic cells or germline cells.
Chromosomal Alterations Are Large-Scale Mutations
While point mutations are changes in a single nucleotide in...