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Updated: May 20, 2026
Synthesis of Near-Infrared Emitting Gold Nanoclusters for Biological Applications
Published on: March 22, 2020
Gold nanocages as contrast agents for two-photon luminescence endomicroscopy imaging
Yongping Chen1, Yuying Zhang, Wenxuan Liang
1Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, USA.
Abstract:
We explored the possibility of using gold (Au) nanocages as a new class of exogenous contrast agents for endomicroscopic nonlinear imaging. The two-photon luminescence cross-section of nanocages was characterized. Two-photon luminescence endomicroscopy imaging of a phantom, cancer cells and biological tissues was performed, demonstrating that Au nanocages can potentially serve as an effective molecular contrast agent for nonlinear endomicroscopy imaging.
From The Clinical Editor:
In this study, the utility of Au nanocages is described in a variety of settings as effective molecular contrast agent for nonlinear endomicroscopy imaging.
