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Updated: May 20, 2026
Non-contact, Label-free Monitoring of Cells and Extracellular Matrix using Raman Spectroscopy
Published on: May 29, 2012
Label-free molecular analysis of live Neospora caninum tachyzoites in host cells by selective scanning Raman
Kenny Kong1, Christopher J Rowlands, Hany Elsheikha
1School of Physics and Astronomy, University of Nottingham, UK.
Abstract:
A selective scanning method was used to measure spatially resolved Raman spectra of live Neospora caninum tachyzoites colonizing human brain microvascular-endothelial cells. The technique allowed the detection of nucleic acids, lipids and proteins linked to the parasites and their cellular micro-environment at ∼10× shorter acquisition time compared to raster scanning.
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