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Updated: May 20, 2026

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Published on: June 2, 2014
How general practitioners treat migraine patients: evaluation of a headache guideline
R Zielman1, Pjl Veenstra, Ew van Zwet
1Department of Neurology, Leiden University Medical Center, the Netherlands.
Aim:
The aim of the study was to evaluate the pharmacological treatment of migraine patients by general practitioners before referral to a neurologist. First, was the pharmacological treatment in accordance with the Dutch College of General Practitioners headache guideline? Second, which migraine characteristics were associated with receiving migraine-specific medication?
Methods:
Migraine patients (age ≥ 18 years) who visited the neurology outpatient clinic for the first time were included. Migraine characteristics and pharmacological status were collected retrospectively for each patient from the general practitioner's referral letter, hospital record and a headache characteristics questionnaire.
Results:
A total of 420 migraine patients were included. Only 18.3% of the patients with two or more migraine attacks per month were using prophylactic medication. Furthermore, only 11.7% of patients with symptoms of nausea and/or vomiting were using anti-emetic medication. More than half of patients (51.7%) were using triptans and were likely to have typical migraine symptoms and a long history of migraine.
Conclusions:
Migraine prophylactic medication and anti-emetics are underutilized in the primary care setting for migraine patients in the Netherlands, when compared to the general practitioners guideline. It is important to enhance the knowledge of general practitioners regarding the diagnosis of migraine, and to increase awareness of the headache guideline.
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