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Intracranial Pharmacotherapy and Pain Assays in Rodents
Published on: April 9, 2019
Management of pain with comorbid substance abuse
Daniel Krashin1, Natalia Murinova, Jane Ballantyne
1Anesthesiology and Pain Medicine, University of Washington Medical Center, Box 354692, 1959 NE Pacific, Seattle, WA 98195, USA. krashind@uw.edu
Abstract:
Substance use disorders are a large public health problem in the United States. Over the past decade, there has been a trend of increased prescription drug misuse, morbidity, and mortality related to prescription opioids. For providers who treat pain, this has led to clinical dilemmas as the newly appreciated risks must be balanced with the benefits of treatment, particularly in patients with known substance use disorders. Acute, chronic, and palliative each present distinct issues in pain treatment. A best practices model of pain treatment, including risk stratification and integrative treatment, may provide the best prospect for safe and effective treatment.
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