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Related Experiment Video

Updated: May 20, 2026

Phenotypic Analysis of Rodent Malaria Parasite Asexual and Sexual Blood Stages and Mosquito Stages

Phenotypic Analysis of Rodent Malaria Parasite Asexual and Sexual Blood Stages and Mosquito Stages

Published on: May 30, 2019

[Malaria in hominids].

Georges Snounou¹, Ananias Escalante, John Kasenene

¹Inserm Umr S945, Université Pierre et Marie Curie, 75013 Paris. georges.snounou@upmc.fr

Bulletin De L'Academie Nationale De Medecine

|August 1, 2012

Summary

Malaria parasites in great apes are poorly understood. Recent studies reveal diverse Plasmodium species in apes, closely related to human malaria parasites, offering insights into Plasmodium falciparum evolution.

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Area of Science:

Primatology
Parasitology
Evolutionary Biology

Context:

Malaria parasites (Plasmodium spp.) infecting great apes are historically understudied.
Previous research focused on limited ape populations and specific Plasmodium species.
Early 20th-century studies described Plasmodium in gorillas, chimpanzees, and orangutans.

Purpose:

To investigate the diversity of Plasmodium species in African great apes.
To understand the evolutionary relationship between ape and human malaria parasites.
To explore the implications for the origin and biology of Plasmodium falciparum.

Summary:

Recent molecular studies reveal unexpected Plasmodium diversity in chimpanzee and gorilla populations.
These ape-infecting Plasmodium species are phylogenetically close to human Plasmodium falciparum.
Observed infections of non-human primates by human malaria parasites provide new data.

Impact:

These findings illuminate the evolutionary history and origin of Plasmodium falciparum.
Provides a unique model system to study the biological specificities of this major human parasite.
Enhances understanding of malaria parasite transmission dynamics and host specificity.