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[A case of propranolol therapy for infantile capillary hemangiomas of the parotis]
Shinya Hirahara1, Keiji Matsuda, Katsuhiro Toyama
1Department of Otorhinolaryngology, Head and Neck Surgery Faculty of medicine, University of Miyazaki.
Insights
Propranolol effectively treated a rapidly growing infantile hemangioma. This safe and efficient treatment led to near-complete tumor disappearance within four months.
Area of Science:
- Pediatric Oncology
- Dermatology
- Vascular Malformations
Background:
- Infantile hemangiomas are common benign vascular tumors.
- Rapidly growing hemangiomas can cause cosmetic and functional issues.
- Treatment options for infantile hemangiomas have evolved.
Abstract:
A 4-month-old healthy female infant presented with rapid onset of subaural swelling over a three-month period. A head and neck exam demonstrated a subaural elastic hard mass with a red birthmark below the left auricle. MRI of the neck demonstrated a well-defined parotid mass consistent with a haemangioma. We treated this infant with 1 mg/kg of propranolol, which was gradually increased over two months to a dose of 2 mg/kg daily. The tumor began to reduce in size within three days after drug administration, and became less prominent in one month, and had almost totally disappeared within four months. On ten-month follow-up, the patient was asymptomatic and repeated MRI demonstrated further regression of the tumor. Propranolol could be the first-line choice for treating haemangioma rather than simple
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