Antibody persistence in splenectomized adults after pneumococcal vaccination
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H B Konradsen1, J L Nielsen, F K Pedersen
1WHO Collaborating Centre for Reference and Research on Pneumococci, Statens Seruminstitut, Copenhagen, Denmark.
Scandinavian Journal of Infectious Diseases
|January 1, 1990
Abstract:
16 splenectomized adults, all vaccinated with a 14-valent pneumococcal vaccine (Pneumovax) 1978-79 had their pneumococcal antibody concentrations measured before and up to 10 years after vaccination. The antibody concentrations after vaccination declined to 71% in 2 years and remained at this level during the 10-year study period. Further studies are needed to see whether this applies to all vaccinated splenectomized adults.