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Utilizing the Antigen Capsid-Incorporation Strategy for the Development of Adenovirus Serotype 5-Vectored Vaccine Approaches
Published on: May 6, 2015
Adenovirus vectors and subviral particles for protein and peptide delivery
Matthias W Kron1, Florian Kreppel
1Department of Gene Therapy, University of Ulm, Helmholtzstr. 8/1, D-89081 Ulm, Germany.
Current Gene Therapy
|August 1, 2012
Abstract:
Adenovirus vectors belong to the most frequently used vector type in gene therapy approaches. In addition, adenovirus vector particles and adenovirus subviral particles offer a great potential for the direct delivery of proteins into cells. In this review we discuss this potential and the technology of adenovirus as a protein delivery platform for applications ranging from vaccination to gene therapy.
