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Can an athlete have too much ticker? Hypertrophic cardiomyopathy in young athletes
Nicholas M Fitzgerald1, Megan Sherwood, Dominic A Fitzgerald
1University of New South Wales Medical School, Sydney, New South Wales, Australia.
Insights
Sudden cardiac death in young athletes is often caused by hypertrophic cardiomyopathy (HCM). Screening for HCM can reduce mortality but incurs substantial economic costs, necessitating a balanced approach to athlete safety and healthcare resources.
Area of Science:
- Cardiology
- Sports Medicine
- Genetics
Background:
- Sudden cardiac death (SCD) is a rare but severe risk in adolescent and young adult athletes.
- Hypertrophic cardiomyopathy (HCM), a genetic heart condition, is the leading cause of SCD in this population.
- HCM is a manageable condition with early diagnosis.
Purpose of the Study:
- To present evidence and arguments for and against screening for HCM in athletes.
- To discuss current screening strategies employed in Europe and North America.
- To outline management strategies for HCM, illustrated with a case study.
Main Methods:
- Review of evidence regarding HCM screening in athletes.
- Analysis of arguments supporting and opposing current screening protocols.
- Presentation of a clinical case to illustrate management.
Main Results:
- Screening and early diagnosis of HCM have demonstrably reduced mortality rates in athletes.
- Current screening strategies differ between Europe and North America.
- Screening programs for HCM are associated with significant economic costs.
Conclusions:
- While screening effectively reduces SCD mortality, its high economic cost requires careful consideration.
- Balancing the benefits of early detection against financial implications is crucial for implementing effective HCM screening programs.
- Further evaluation of screening strategies and management protocols for HCM in athletes is warranted.
Abstract:
Sudden cardiac death (SCD) is an uncommon but devastating potential consequence of participation in competitive sport. It is seen in adolescent and young adult athletes. The most common cause of this, hypertrophic cardiomyopathy (HCM), is a genetic disorder responsible for more than a third of cases and is manageable. Screening is undertaken for HCM, using differing strategies in Europe and North America. Screening and early diagnosis have reduced the mortality rate but has come at a significant economic cost. The evidence and relevant arguments for and against screening are presented together with management strategies as reflected by an illustrative case.
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