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Endurance exercise training in patients with small abdominal aortic aneurysm: a randomized controlled pilot study
Garry A Tew1, James Moss, Helen Crank
1Centre for Sport and Exercise Science, Sheffield Hallam University, Sheffield, UK. g.tew@shu.ac.uk
Archives of Physical Medicine and Rehabilitation
|August 1, 2012
Summary
Moderate-intensity endurance exercise is feasible for patients with small abdominal aortic aneurysms (AAA). This training improved cardiopulmonary fitness and reduced vascular risk markers without adverse events.
Area of Science:
- Cardiovascular Medicine
- Exercise Physiology
- Vascular Surgery
Background:
- Small abdominal aortic aneurysms (AAA) pose a risk, and exercise recommendations are often conservative.
- Investigating safe and effective interventions for patients with small AAA is crucial.
Purpose of the Study:
- To assess the feasibility of a 12-week moderate-intensity endurance exercise program in patients with small AAA.
- To gather preliminary data on the impact of exercise on cardiopulmonary fitness, quality of life, and vascular risk markers.
Main Methods:
- A randomized controlled pilot study involving 28 patients with small AAA.
- Participants were assigned to either an endurance exercise program or standard care.
- Outcomes included safety (AAA size, adverse events), ventilatory threshold, quality of life (SF-36), blood pressure, and hs-CRP.
Main Results:
- The exercise program was feasible with 94% adherence and no adverse events or AAA expansion.
- Significant improvements in ventilatory threshold (2.5 mL·kg(-1)·min(-1)) were observed in the exercise group.
- Reductions in systolic blood pressure and high-sensitivity C-reactive protein (hs-CRP) were noted in the exercise group compared to controls.
Conclusions:
- Moderate-intensity endurance exercise training is a feasible and safe intervention for patients with small AAA.
- Exercise can lead to improvements in cardiovascular fitness and vascular health markers in this population.
- Despite a low recruitment rate, the study provides promising preliminary evidence for exercise as a beneficial intervention.
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