[Perfusion computed tomography for diffuse liver diseases]
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Updated: May 20, 2026
An Open-Source Normothermic Perfusion System Designed for Research Scientists
Published on: July 18, 2025
1Klinik für Diagnostische und Interventionelle Radiologie, Universitätsklinikum Ulm, Albert-Einstein-Allee 23, Ulm, Germany. stefan.schmidt@uniklinik-ulm.de
Clinical/Methodical Issue:
Perfusion computed tomography (CT) has its main application in the clinical routine diagnosis of neuroradiological problems.
Standard Radiological Methods:
Polyphase multi-detector spiral computed tomography is primarily used in liver diagnostics.
Methodical Innovations:
The use of perfusion CT is also possible for the diagnostics and differentiation of diffuse hepatic diseases.
Performance:
The differentiation between cirrhosis and cirrhosis-like parenchymal changes is possible. It also helps to detect early stages of malignant tumors.
Achievements:
However, there are some negative aspects, particularly that of radiation exposure.
Practical Recommendations:
This paper summarizes the technical basics and possible applications of perfusion CT in cases of diffuse liver disease and weighs up the advantages and disadvantages of the examinations.
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