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Published on: August 14, 2013

Elevated NEFA levels impair glucose effectiveness by increasing net hepatic glycogenolysis

S Kehlenbrink1, S Koppaka, M Martin

  • 1Division of Endocrinology, Department of Medicine, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA.

Diabetologia
|August 1, 2012
PubMed
Summary

Acute hyperglycemia normally suppresses glucose production in non-diabetics. In type 2 diabetes, elevated non-esterified fatty acids (NEFA) impair this glucose effectiveness, leading to higher blood sugar.

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