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Related Concept Videos

Diabetic Neuropathy01:22

Diabetic Neuropathy

DefinitionDiabetic neuropathy is nerve damage caused by long-standing diabetes mellitus. It results directly from prolonged high blood sugar levels.PathophysiologyThe pathophysiology of diabetic neuropathy involves both metabolic and vascular disturbances triggered by chronic hyperglycemia.Metabolic injury: Elevated glucose levels activate the polyol pathway within nerve cells, leading to the accumulation of sorbitol and fructose. This increases oxidative stress, disrupts normal nerve...
Diabetic Retinopathy01:27

Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
Diabetic Foot Ulcer01:31

Diabetic Foot Ulcer

Definition A diabetic foot ulcer (DFU) is a chronic, non-healing wound that develops in individuals with diabetes. It typically occurs on pressure-bearing areas such as the heel, metatarsal heads, or hallux, and carries a high risk of infection and amputation.Pathophysiology • The development of DFUs can be explained by four interconnected mechanisms: neuropathy, ischemia, infection, and impaired wound healing. • Neuropathy is the most common factor. Sensory neuropathy reduces pain perception,...
Type I Diabetes III: Clinical Manifestations01:19

Type I Diabetes III: Clinical Manifestations

Type 1 diabetes mellitus typically presents with rapid-onset symptoms due to the body’s inability to utilize glucose in the absence of insulin. Since insulin is required for glucose uptake into cells, its deficiency leads to hyperglycemia and cellular energy deprivation, resulting in characteristic clinical features.Polyuria and PolydipsiaOne of the earliest, most prominent symptoms is polyuria (excessive urination). When blood glucose concentrations rise above the renal threshold, the kidneys...
Diabetic Nephropathy01:28

Diabetic Nephropathy

Definition Diabetic nephropathy is a chronic kidney complication that results from prolonged hyperglycemia.Prevalence It is the most common cause of chronic kidney disease (CKD) and end-stage renal disease (ESRD) worldwide, affecting up to half of individuals with diabetes.Pathophysiology • Sustained hyperglycemia triggers multiple hemodynamic and metabolic changes in the kidney. • Early in the disease, increased renal blood flow and glomerular hyperfiltration occur due to afferent arteriolar...
Type II Diabetes Mellitus III: Clinical Manifestations and Diagnosis01:25

Type II Diabetes Mellitus III: Clinical Manifestations and Diagnosis

Type 2 diabetes mellitus develops gradually and is often asymptomatic in early stages.Clinical ManifestationsWhen symptoms appear, they include fatigue, blurred vision, pruritus, delayed wound healing, and recurrent infections, particularly candidal infections. Peripheral neuropathy may present as numbness or tingling in the extremities. Classic hyperglycemia symptoms—polyuria, polydipsia, and polyphagia—are less common. Most patients are overweight and frequently have associated hypertension...

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Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
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Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction

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Diabetic mastopathy.

Smita Sankaye1, Sushil Kachewar

  • 1DiabeticSenior Resident in Pathology, Rural Medical College, PIMS, Loni, India.

The Australasian Medical Journal
|August 1, 2012
PubMed
Summary
This summary is machine-generated.

Diabetic mastopathy, a condition linked to long-standing diabetes, presents as benign breast tissue inflammation and fibrosis. Recognizing this non-cancerous condition can prevent unnecessary biopsies and surgeries in diabetic patients.

Keywords:
B-­‐lymphocytesBreast cancerBreast massDiabetes mellitusDiabetic mastopathyLymphocytic mastitisMastopathy

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Orthotopic Injection of Breast Cancer Cells into the Mice Mammary Fat Pad
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Published on: January 20, 2019

Area of Science:

  • Endocrinology
  • Pathology
  • Radiology

Background:

  • Diabetic mastopathy is a benign breast condition associated with long-standing diabetes mellitus.
  • It involves lymphocytic mastitis and stromal fibrosis, affecting both men and women.
  • The condition can mimic malignant breast lesions clinically and radiologically.

Observation:

  • A case presentation of diabetic mastopathy is detailed.
  • The clinical and radiological features are highlighted.
  • The potential for recurrence of diabetic mastopathy is noted.

Findings:

  • Diabetic mastopathy can be mistaken for breast cancer.
  • Unnecessary biopsies may be performed due to suspicion of malignancy.
  • Failure to diagnose diabetic mastopathy can lead to adverse outcomes.

Implications:

  • Accurate recognition of diabetic mastopathy is crucial for avoiding invasive procedures.
  • Increased awareness can prevent unnecessary surgical interventions.
  • Early and correct diagnosis aids in patient management and reduces patient distress.