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Hyperglycemia

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Hyperglycemia is an abnormally high blood glucose level. It is diagnosed by fasting glucose ≥126 mg/dL, 2-hour oral glucose tolerance test (or OGTT) ≥200 mg/dL, random glucose ≥200 mg/dL with symptoms, or HbA1c ≥6.5%. However, HbA1c results may be unreliable in certain conditions, such as anemia or hemoglobinopathies, and the diagnosis should be confirmed unless classic symptoms are present. Postprandial hyperglycemia is typically considered significant when glucose levels exceed 180 mg/dL two...

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Related Experiment Video

Updated: May 20, 2026

Study of In Vivo Glucose Metabolism in High-fat Diet-fed Mice Using Oral Glucose Tolerance Test (OGTT) and Insulin Tolerance Test (ITT)

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[Association between hyperuricemia and insulin resistance].

Estela Abreu¹, Maria João Fonseca, Ana Cristina Santos

¹Departamento de Epidemiologia Clínica, Medicina Preditiva e Saúde Pública, Faculdade de Medicina da Universidade do Porto, Instituto de Saúde Pública da Universidade do Porto, Porto, Portugal.

Acta Medica Portuguesa

|August 2, 2012

Summary

Hyperuricemia, a condition of high uric acid levels, is linked to insulin resistance (IR) in Portuguese adults. This association is particularly strong in men and increases with higher uric acid levels in both genders.

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Area of Science:

Endocrinology
Metabolic Syndrome
Public Health

Context:

Insulin resistance (IR) is a known cardiovascular risk factor.
The relationship between IR and hyperuricemia is less understood.
Prevalence of hyperuricemia and its association with IR in Portuguese adults requires investigation.

Purpose:

To determine the prevalence of hyperuricemia in a Portuguese adult community sample.
To assess the association between hyperuricemia and insulin resistance (IR).

Summary:

A health survey of 1370 Portuguese adults found hyperuricemia prevalence at 12.8%.
Hyperuricemia was associated with a higher prevalence of IR (OR=1.84).
This association was stronger in men and increased with higher uric acid levels in both genders.

Impact:

Findings highlight hyperuricemia as a potential indicator for IR.
Suggests a need for further research into the mechanisms linking uric acid and IR.
Informs public health strategies for metabolic syndrome risk assessment.