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Model systems to study immunomodulation in domestic food animals
1Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames 50011.
Advances in Veterinary Science and Comparative Medicine
|January 1, 1990
Summary
Developing immunomodulators for food animals is crucial for combating diseases like bovine respiratory disease. Research using immunosuppression models shows these modulators can significantly boost animal resistance to key infectious diseases.
Area of Science:
- Veterinary Immunology
- Animal Health
- Immunomodulation
Background:
- Immunomodulators are being developed for food-producing animals.
- Research often uses immunosuppression models to study disease pathogenesis.
- Key targets include stress-associated diseases, young animal infections, and mastitis.
Purpose of the Study:
- To review the development of immunomodulators for food animals.
- To highlight the role of immunosuppression models in this research.
- To discuss the potential of immunomodulators in disease resistance.
Main Methods:
- Review of existing research on immunomodulators in food animals.
- Analysis of studies employing immunosuppression models.
- Focus on economically significant diseases and their pathogenesis.
Main Results:
- Immunosuppression models have been instrumental in developing immunomodulators.
- These models have demonstrated the efficacy of immunomodulators in increasing disease resistance.
- Significant progress has been made in addressing bovine respiratory disease, infections in young animals, and mastitis.
Conclusions:
- Immunomodulators show promise for enhancing disease resistance in food animals.
- Relevant model systems are vital for advancing immunomodulation research.
- Continued research, aided by increased understanding of molecular immunology, will drive future developments.