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Related Concept Videos

Overview of Protein Metabolism01:21

Overview of Protein Metabolism

Proteins are broken down into amino acids during digestion. Unlike fats and carbohydrates, which are stored for later use, proteins are not. Instead, amino acids are either used to produce ATP through oxidation or contribute to the creation of new proteins for the growth and repair of the body. Any surplus amino acids from the diet are converted into glucose or triglycerides rather than excreted.
Amino acids play various roles in the body once they are absorbed into cells. They are restructured...
Nephrotic Syndrome I : Introduction01:24

Nephrotic Syndrome I : Introduction

Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of fluid...
Cirrhosis I: Introduction01:23

Cirrhosis I: Introduction

Cirrhosis is a chronic, irreversible liver disease characterized by the widespread replacement of healthy liver tissue with fibrotic scar tissue and the formation of regenerative nodules.Etiology of cirrhosisCirrhosis results from sustained liver injury that triggers progressive fibrosis and structural remodeling. The underlying causes are diverse, encompassing common and less frequent clinical conditions. Regardless of the origin, all causes lead to chronic inflammation, hepatocyte loss, and...
Nephrotic Syndrome II : Assessment and Medical Management01:26

Nephrotic Syndrome II : Assessment and Medical Management

IntroductionNephrotic syndrome is a kidney disorder marked by excessive protein loss in the urine, leading to various systemic complications. This condition often results from damage to the glomeruli—the kidney's filtering units—causing proteinuria, low blood protein levels, and fluid retention. Understanding the assessment, diagnosis, and management of nephrotic syndrome is essential for effective treatment and prevention of further kidney damage.AssessmentPatient History: Document any history...
Nephrotic Syndrome III : Nursing Management01:24

Nephrotic Syndrome III : Nursing Management

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Related Experiment Videos

Malnutrition in systemic sclerosis.

Elizabeth Harrison1, Ariane L Herrick, John T McLaughlin

  • 1Department of Gastroenterology, Salford Royal NHS Foundation Trust, Salford, UK. mmmckeh2@doctors.org.uk

Rheumatology (Oxford, England)
|August 2, 2012
PubMed
Summary
This summary is machine-generated.

Systemic sclerosis (SSc) often causes malnutrition, increasing morbidity and mortality. Specialist knowledge is needed for effective nutritional screening and interventions in SSc patients.

Related Experiment Videos

Area of Science:

  • Rheumatology
  • Gastroenterology
  • Clinical Nutrition

Background:

  • Systemic sclerosis (SSc) is a chronic, multi-system autoimmune disease.
  • Gastrointestinal (GI) manifestations affect over 90% of SSc patients, contributing to significant morbidity.
  • Nutritional decline and malnutrition are common, increasing mortality and reliance on nutritional support.

Purpose of the Study:

  • To review current knowledge on malnutrition in SSc.
  • To highlight the impact of GI manifestations on nutritional status.
  • To emphasize the need for specialized management strategies for SSc-related malnutrition.

Main Methods:

  • Literature review of studies on SSc, GI disease, and malnutrition.
  • Analysis of existing data on nutritional screening tools like Malnutrition Universal Screening Tool (MUST).
  • Examination of reported nutritional interventions and their outcomes in SSc.

Main Results:

  • Up to 18% of SSc patients are at high risk of malnutrition, with risk correlating to disease severity.
  • GI dysfunction significantly contributes to nutritional decline and complications like intestinal failure.
  • Limited data exists on the progression of malnutrition and the effectiveness of specific SSc nutritional interventions.

Conclusions:

  • Effective management of SSc requires addressing GI complications and nutritional decline.
  • There is a critical need for developing specialized knowledge and interventions for malnutrition in SSc.
  • Improved nutritional screening and tailored interventions are essential to reduce morbidity and mortality in SSc patients.