Related Experiment Video
Updated: May 20, 2026
An Experimental Model of Diet-Induced Metabolic Syndrome in Rabbit: Methodological Considerations, Development, and Assessment
Published on: April 20, 2018
Impact of flaxseed intake upon metabolic syndrome indicators in female Wistar rats
Lívia Hipólito Cardozo Brant1, Ludmila Ferreira Medeiros de França Cardozo, Luís Guillermo Coca Velarde
1Department of Nutrition and Dietetic, UFF, Niteroi-RJ, Brazil. liviahipolito@gmail.com
Purpose:
To evaluate whether the prolonged consumption of flaxseed minimize the factors that trigger MS in healthy rats.
Methods:
Pregnant rats were divided immediately after delivery into two groups during the lactation period, a control group (CG) receiving casein-based diet with 17% of protein, and a Flaxseed group (FG) with casein-based diet plus 25% of flaxseed. At weaning, 12 offspring of each group continued to receive the same feed but with 10% of protein up to 200 days old.
Results:
FG showed a significant reduction in body weight (p=0.001), total cholesterol levels (p<0.0001), triglycerides (p=0.0001), and glucose (p=0.001).
Conclusion:
The flaxseed alters the indicators related to development of metabolic syndrome, because it has beneficial effects on lipids and glucose profiles and prevents the excess of body weight gain.
