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Related Experiment Video

Updated: May 19, 2026

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels

Published on: August 7, 2017

Rhinologic issues in pregnancy.

Gregg Goldstein¹, Satish Govindaraj

¹Department of Otolaryngology-Head and Neck Surgery, Mount Sinai School of Medicine, New York, New York.

Allergy & Rhinology (Providence, R.I.)

|August 2, 2012

Summary

This summary is machine-generated.

Managing sinonasal conditions like rhinitis, sinusitis, and epistaxis in pregnant patients requires careful consideration. Evidence-based guidelines are crucial for safe and effective treatment, balancing maternal health with fetal well-being.

Keywords:

Advair Augmentin albuterol allergic rhinitis amoxicillin anaphylaxis azithromycin budesonide epistaxis fluticasone gestational rhinitis montelukast prednisone pyogenic granuloma rads rhinitis medicamentosa rhinitis of pregnancy sinusitis

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Published on: September 22, 2023

Area of Science:

Otolaryngology
Obstetrics
Pharmacology

Background:

Sinonasal diseases (rhinitis, sinusitis, epistaxis) pose unique challenges during pregnancy.
Poorly controlled conditions can negatively impact maternal quality of life and pregnancy outcomes.
Limited safety data hinders informed clinical decision-making for pregnant patients.

Purpose of the Study:

To review current literature and evidence-based guidelines for managing sinonasal disease in pregnant patients.
To familiarize clinicians with diagnostic and therapeutic options, including imaging, medical, and surgical interventions.
To highlight safety considerations for both mother and fetus.

Main Methods:

A comprehensive review of pertinent guidelines for gestational rhinitis, sinusitis, and epistaxis.
Analysis of diagnostic and therapeutic limitations specific to pregnancy physiology.
Case study analysis of four pregnant patients with sinonasal conditions.

Main Results:

Two cases of epistaxis and two of rhinosinusitis were analyzed (16-35 weeks gestation).
Management strategies were evaluated based on patient history, examination, clinical course, and operative reports.
The review identified key considerations for treatment during pregnancy.

Conclusions:

Treating sinonasal disease in pregnancy is complex, necessitating a thorough understanding of medical evidence and guidelines.
Optimizing maternal health while minimizing fetal risk is paramount.
Limited, safe interventions should be prioritized when delaying treatment is not feasible.