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Effect of food on absorption of lomefloxacin
W D Hooper1, R G Dickinson, M J Eadie
1Department of Medicine, University of Queensland, Royal Brisbane Hospital, Herston, Australia.
Antimicrobial Agents and Chemotherapy
|September 1, 1990
Abstract:
Twelve subjects participated in an open-label, single-dose, balanced three-way crossover study in which the absorptions of lomefloxacin were compared following (i) an overnight fast, (ii) a carbohydrate meal, and (iii) a high-fat meal. The time to peak concentration of lomefloxacin was delayed, but peak concentration in plasma and amount of drug absorbed were unchanged following both meals.