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Updated: May 19, 2026

Retinal Pathophysiological Evaluation in a Rat Model
Published on: May 6, 2022
Diabetic angiopathy and angiogenic defects
Ling Xu1, Keizo Kanasaki, Munehiro Kitada
1Division of Diabetology & Endocrinology, Kanazawa Medical University, Uchinada, Ishikawa, 920-0293, Japan. kkanasak@kanazawa-med.ac.jp.
Abstract:
Diabetes is one of the most serious health problems in the world. A major complication of diabetes is blood vessel disease, termed angiopathy, which is characterized by abnormal angiogenesis. In this review, we focus on angiogenesis abnormalities in diabetic complications and discuss its benefits and drawbacks as a therapeutic target for diabetic vascular complications. Additionally, we discuss glucose metabolism defects that are associated with abnormal angiogenesis in atypical diabetic complications such as cancer.
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