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Related Experiment Video

Updated: May 19, 2026

The Establishment of a Murine Maxillary Orthodontic Model

The Establishment of a Murine Maxillary Orthodontic Model

Published on: October 27, 2023

Changes in overnight arterial oxygen saturation after mandibular setback.

Tadaharu Kobayashi¹, Akinori Funayama, Daichi Hasebe

¹Division of Reconstructive Surgery for Oral and Maxillofacial Region, Department of Tissue Regeneration and Reconstruction, Course for Oral Life Science, Niigata University Graduate School of Medical and Dental Sciences, 2-5274 Gakkocho-Dori, Cyuo-Ku, Niigata City 951-8514, Japan. tadaharu@dent.niigata-u.ac.jp

The British Journal of Oral & Maxillofacial Surgery

|August 3, 2012

Summary

This summary is machine-generated.

Mandibular setback surgery may temporarily worsen airway space and breathing during sleep. However, most patients adapt well, with no sleep-disordered breathing evident after six months. Obese patients require closer monitoring post-surgery.

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A Model to Simulate Clinically Relevant Hypoxia in Humans

A Model to Simulate Clinically Relevant Hypoxia in Humans

Published on: December 22, 2016

Area of Science:

Oral and Maxillofacial Surgery
Sleep Medicine
Respiratory Physiology

Background:

Mandibular setback surgery, used to correct skeletal Class III malocclusions, can reduce pharyngeal airway space.
Concerns exist regarding the potential induction of sleep-disordered breathing (SDB) following this procedure.

Purpose of the Study:

To investigate the effects of mandibular setback on pharyngeal airway space and respiratory function during sleep.
To evaluate the incidence and progression of sleep-disordered breathing post-surgery.

Main Methods:

Seventy-eight patients with skeletal Class III malocclusions underwent mandibular setback.
Lateral cephalograms assessed airway morphology preoperatively, immediately postoperatively, and >6 months postoperatively.
Overnight pulse oximetry measured arterial oxygen saturation (SpO2) and calculated oximetric indices at multiple time points.

Main Results:

Immediate postoperative SpO2 levels were significantly lower than preoperative levels, but gradually improved.
Positive correlations were found between Body Mass Index (BMI) and oximetric indices.
Little association was observed between changes in mandibular position and oximetric indices.

Conclusions:

While most patients adapt to altered airway dimensions, some, particularly those with obesity, may experience transient sleep-disordered breathing shortly after surgery.
Close monitoring of respiratory function during sleep is crucial in the immediate postoperative period, especially for at-risk individuals.
Long-term follow-up is recommended to ensure adaptation and rule out persistent SDB.