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Autoinflammatory syndromes: fever is not always a sign of infection
Andrew S Zeft1, Steven J Spalding
1Center for Pediatric Rheumatology and Immunology, Cleveland Clinic, Cleveland, OH 44195, USA. zefta@ccf.org
Abstract:
Autoinflammatory syndromes are a newly understood group of conditions characterized by recurrent episodes of fever, rash, and serositis. Generalists and specialists should know about and consider these syndromes in the differential diagnosis of recurrent fever. This article reviews the genetics, pathophysiology, clinical presentation, and treatment of several of these relatively recently discovered diseases.
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