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ARHAI: antiviral resistance

C Y William Tong1, Patricia A Cane, Deenan Pillay

  • 1Department of Infectious Diseases, Guy's and St Thomas' NHS Foundation Trust and King's College London School of Medicine, 5th Floor North Wing, St Thomas' Hospital, London SE1 7EH, UK. william.tong@gstt.nhs.uk

The Journal of Antimicrobial Chemotherapy
|August 3, 2012
PubMed

Insights

Monitoring antiviral resistance in the UK is crucial for public health. This study focused on tracking resistance in influenza, HIV, and hepatitis viruses through a coordinated laboratory network.

Area of Science:

  • Infectious Diseases
  • Microbiology
  • Public Health

Background:

  • Antiviral resistance poses a significant threat, particularly to the Advisory Committee on Antimicrobial Resistance and Healthcare-Associated Infections (ARHAI).
  • The United Kingdom has dedicated substantial resources over the past four years to establish robust monitoring systems for antiviral resistance.
  • Key targets for surveillance include resistance to antiviral agents in influenza virus, Human Immunodeficiency Virus (HIV), and Hepatitis B and C viruses.

Purpose of the Study:

  • To assess the UK's capability in monitoring the emergence and spread of antiviral resistance.
  • To identify key viral targets for resistance surveillance programs.

Main Methods:

  • Focus on establishing a network of laboratories capable of performing diagnostic tests for antiviral resistance.
  • Implementation of surveillance programs coordinated through a central reference facility within the Health Protection Agency (HPA) or a collaborative study group.

Main Results:

  • Development of a framework for monitoring antiviral resistance across critical viral pathogens.
  • Identification of specific viruses (influenza, HIV, Hepatitis B/C) as priorities for resistance surveillance.

Conclusions:

  • A coordinated laboratory network is essential for effective surveillance of antiviral resistance in the UK.
  • Ongoing monitoring and surveillance are vital to manage the threat of antiviral resistance to public health.

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