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Related Experiment Video

Updated: May 19, 2026

An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings

An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings

Published on: March 30, 2014

ARHAI: antiviral resistance.

C Y William Tong¹, Patricia A Cane, Deenan Pillay

¹Department of Infectious Diseases, Guy's and St Thomas' NHS Foundation Trust and King's College London School of Medicine, 5th Floor North Wing, St Thomas' Hospital, London SE1 7EH, UK. william.tong@gstt.nhs.uk

The Journal of Antimicrobial Chemotherapy

|August 3, 2012

Summary

Monitoring antiviral resistance in the UK is crucial for public health. This study focused on tracking resistance in influenza, HIV, and hepatitis viruses through a coordinated laboratory network.

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Area of Science:

Infectious Diseases
Microbiology
Public Health

Background:

Antiviral resistance poses a significant threat, particularly to the Advisory Committee on Antimicrobial Resistance and Healthcare-Associated Infections (ARHAI).
The United Kingdom has dedicated substantial resources over the past four years to establish robust monitoring systems for antiviral resistance.
Key targets for surveillance include resistance to antiviral agents in influenza virus, Human Immunodeficiency Virus (HIV), and Hepatitis B and C viruses.

Purpose of the Study:

To assess the UK's capability in monitoring the emergence and spread of antiviral resistance.
To identify key viral targets for resistance surveillance programs.

Main Methods:

Focus on establishing a network of laboratories capable of performing diagnostic tests for antiviral resistance.
Implementation of surveillance programs coordinated through a central reference facility within the Health Protection Agency (HPA) or a collaborative study group.

Main Results:

Development of a framework for monitoring antiviral resistance across critical viral pathogens.
Identification of specific viruses (influenza, HIV, Hepatitis B/C) as priorities for resistance surveillance.

Conclusions:

A coordinated laboratory network is essential for effective surveillance of antiviral resistance in the UK.
Ongoing monitoring and surveillance are vital to manage the threat of antiviral resistance to public health.