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Dermatoglyphics in patients with hypothyreosis
Jelena Vucak Kulić1, Jasna Milicić, Damir Letinić
1Zadar General Hospital, Internal Medicine Department, Zadar, Croatia. jelenaby23@yahoo.com
Collegium Antropologicum
|August 4, 2012
Summary
Hypothyroidism, a common thyroid disease, may have genetic links. Fingerprint analysis revealed differences between affected and healthy females, suggesting genetic predisposition.
Area of Science:
- Endocrinology
- Genetics
- Dermatoglyphics
Background:
- Hypothyroidism affects 15% of females and 3% of males.
- Autoimmune thyroid disease is prevalent in Croatia, accounting for 90% of cases.
- Thyroid diseases result from genetic and external factors, with some genetic influences understudied.
Purpose of the Study:
- To investigate the correlation between digito-palmar dermatoglyphics and hypothyroidism.
- To explore the role of genetic predisposition in hypothyroidism using dermatoglyphic analysis.
Main Methods:
- Comparative analysis of qualitative and quantitative dermatoglyphic traits.
- Study groups: 50 females with hypothyroidism and 100 healthy females.
- Statistical analyses included t-test, discriminant analysis, and factor analysis.
Main Results:
- Discriminant analysis achieved 76.9% correct sample classification.
- Factor analysis indicated high variance and differing factor structures in hypothyroid patients.
- Qualitative dermatoglyphic analysis revealed heterogeneity between groups, with qualitative traits being more unstable than quantitative ones.
Conclusions:
- Digito-palmar dermatoglyphics show potential as indicators for hypothyroidism.
- The findings suggest an instability in genes associated with hypothyroidism development, implying a genetic predisposition.
- Further research into genetic factors influencing hypothyroidism is warranted.
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