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Updated: May 19, 2026

High-throughput Identification of Synergistic Drug Combinations by the Overlap2 Method
Published on: May 21, 2018
[Overlap syndrome]
Joana Parente1, Palmira Mathurdas, Luísa Wandschneider
1Serviços de Dermatologia e de Medicina Interna 2, Hospital Distrital de Santarém, Santarém, Portugal.
Abstract:
The overlap syndromes are characterized by the occurrence in the same patient of two or more autoimmune diseases. The overlap syndrome between scleroderma and polymyositis is rare. We describe a case of a 58-year-old woman in which the clinical expression, the effect of therapy and the evolution, support the concept that this syndrome is a distinct clinical entity in the spectrum of autoimmune disease.
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