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Is the APLS formula used to calculate weight-for-age applicable to a Trinidadian population?
Khalid Ali1, Ian Sammy, Paula Nunes
1Eric Williams Medical Sciences Complex, Champs Fleurs, Trinidad, West Indies.
Insights
The APLS formula slightly underestimates children's weight in Trinidad, but remains recommended for paediatric resuscitation due to its familiarity and ease of use. Other formulas offer better estimates but show no significant accuracy difference.
Area of Science:
- Paediatric Emergency Medicine
- Clinical Paediatrics
- Medical Calculations
Background:
- Accurate weight estimation is crucial for drug and fluid dosing in paediatric emergency medicine.
- The APLS (Advanced Paediatric Life Support) weight estimation formula is widely used but may underestimate children's weight.
- The APLS formula's validity in Trinidad and Tobago for paediatric resuscitation has not been previously established.
Purpose of the Study:
- To evaluate the accuracy of the APLS weight estimation formula in children aged one to five years in Trinidad.
- To compare the APLS formula with the Luscombe and Owens formula and a newly derived linear regression formula.
- To determine the most appropriate weight estimation formula for paediatric resuscitation in Trinidad.
Main Methods:
- A prospective study was conducted over six weeks in January 2009.
- Measured weights of children aged one to five years presenting to the Emergency Department were recorded.
- Measured weights were compared against estimated weights from the APLS formula, Luscombe and Owens formula, and a derived linear regression formula.
Main Results:
- The APLS formula underestimated weight, with a mean difference of -1.4 kg.
- The Luscombe and Owens formula showed a smaller underestimation, with a mean difference of -0.4 kg.
- A derived formula (weight = [2.5 x age] + 8) provided the best fit, but all formulas had non-significantly different accuracy and precision.
Conclusions:
- The APLS formula slightly underestimates children's weights in Trinidad, less so than in developed countries.
- The Luscombe and Owens and derived formulas offer better weight estimates for children in Trinidad.
- Despite better estimates from other formulas, the APLS formula is recommended for continued use in Trinidad due to its established recognition and simplicity.
Background:
In paediatric emergency medicine, estimation of weight in ill children can be performed in a variety of ways. Calculation using the 'APLS' formula (weight = [age + 4] × 2) is one very common method. Studies on its validity in developed countries suggest that it tends to under-estimate the weight of children, potentially leading to errors in drug and fluid administration. The formula is not validated in Trinidad and Tobago, where it is routinely used to calculate weight in paediatric resuscitation.
Methods:
Over a six-week period in January 2009, all children one to five years old presenting to the Emergency Department were weighed. Their measured weights were compared to their estimated weights as calculated using the APLS formula, the Luscombe and Owens formula and a "best fit" formula derived (then simplified) from linear regression analysis of the measured weights.
Results:
The APLS formula underestimated weight in all age groups with a mean difference of -1.4 kg (95% limits of agreement 5.0 to -7.8). The Luscombe and Owens formula was more accurate in predicting weight than the APLS formula, with a mean difference of -0.4 kg (95% limits of agreement 6.9 to -6.1%). Using linear regression analysis, and simplifying the derived equation, the best formula to describe weight and age was (weight = [2.5 x age] + 8). The percentage of children whose actual weight fell within 10% of the calculated weights using any of the three formulae was not significantly different.
Conclusions:
The APLS formula slightly underestimates the weights of children in Trinidad, although this is less than in similar studies in developed countries. Both the Luscombe and Owens formula and the formula derived from the results of this study give a better estimate of the measured weight of children in Trinidad. However, the accuracy and precision of all three formulae were not significantly different from each other. It is recommended that the APLS formula should continue to be used to estimate the weight of children in resuscitation situations in Trinidad, as it is well known, easy to calculate and widely taught in this setting.
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