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Updated: May 19, 2026

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder
Published on: April 26, 2024
Prior sleep problems predict internalising problems later in life
Evelyne Touchette1, Aude Chollet, Cédric Galéra
1CESP, INSERM U1018, Epidemiology of Occupational and Social Determinants of Health, F-94807, Villejuif, France. eveline.touchette.1@ulaval.ca
Childhood sleep problems significantly increase the risk of persistent internalizing symptoms, such as depression and anxiety, into adulthood. This 18-year study highlights the long-term impact of early sleep disturbances on mental health.
Area of Science:
- Developmental Psychology
- Child Psychiatry
- Longitudinal Studies
Background:
- Poor sleep affects up to 40% of children, potentially serving as an early risk marker for internalizing symptoms.
- This study examines the predictive relationship between childhood sleep problems and adult internalizing symptoms over an 18-year period.
Purpose of the Study:
- To investigate whether sleep problems in childhood predict the development and persistence of internalizing symptoms into adulthood.
- To analyze trajectories of internalizing symptoms over 18 years in relation to early sleep issues.
Main Methods:
- A longitudinal study of 1503 French young adults (TEMPO cohort) with data collected in 1991, 1999, and 2009.
- Sleep problems and internalizing symptoms (depression, anxiety, somatic complaints) were assessed using the Achenbach System of Empirically Based Assessment (ASEBA).
- Multinomial logistic regression was used to analyze the association between 1991 sleep problems and internalizing symptom trajectories, controlling for covariates.
Main Results:
- Four trajectories of internalizing symptoms were identified: high-persistent (2.5%), high-decreasing (11.4%), low-increasing (11.6%), and low-persistent (74.5%).
- Children with sleep problems in 1991 were significantly more likely to experience high-persistent (4.51 times) and high-decreasing (3.69 times) internalizing symptoms over the 18-year follow-up, after controlling for covariates.
Conclusions:
- Early-life sleep problems are associated with a substantially increased likelihood of internalizing symptoms persisting from childhood through adulthood.
- Findings underscore the importance of addressing childhood sleep issues as a potential preventative measure for long-term mental health problems.
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