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Updated: May 19, 2026

Corneal Epithelial Abrasion with Ocular Burr As a Model for Cornea Wound Healing
Published on: July 10, 2018
Topical nonsteroidal anti-inflammatory drugs for corneal abrasions in children
Insights
Topical nonsteroidal anti-inflammatory drugs (NSAIDs) effectively relieve pain from corneal abrasions in children. However, rare serious complications are noted in adults, necessitating careful monitoring for all patients.
Area of Science:
- Ophthalmology
- Pharmacology
- Pediatric Medicine
Background:
- Corneal abrasions are frequent eye injuries in pediatric and adult populations.
- Topical nonsteroidal anti-inflammatory drugs (NSAIDs) are sometimes prescribed for pain relief in these cases.
- The safety and efficacy of this practice warrant further investigation, particularly in children.
Purpose of the Study:
- To evaluate the safety and effectiveness of topical ophthalmic NSAIDs for managing pain associated with corneal abrasions.
- To assess potential risks and benefits in both pediatric and adult patients.
Main Methods:
- Review of existing literature and case studies on topical NSAID use for corneal abrasions.
- Analysis of reported efficacy for pain management.
- Examination of documented adverse events and complications.
Main Results:
- Topical ophthalmic NSAIDs demonstrate short-term efficacy in alleviating pain from corneal abrasions in children.
- Case studies in adults report rare but serious complications associated with topical NSAID use.
- No specific pediatric complications were detailed, but the potential for adverse effects exists.
Conclusions:
- Topical NSAIDs are an effective short-term pain management strategy for pediatric corneal abrasions.
- Physicians must be aware of rare, serious complications reported in adults.
- Close follow-up (24-48 hours) is crucial for children treated with topical NSAIDs to monitor healing and side effects.
Question:
Corneal abrasion from minor injury to the eye is common in both adults and children. Some of my colleagues prescribe topical nonsteroidal anti-inflammatory drugs (NSAIDs) for analgesia. How safe is this practice?
Answer:
Topical ophthalmic NSAIDs are a short-term effective treatment of the pain associated with corneal abrasions in children. Rare but serious complications have been reported in adult case-study series. Children with corneal abrasions should have follow-up appointments within 24 to 48 hours to assess healing, complications, and side effects of treatment, particularly if they are using topical NSAIDs.
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