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Updated: May 19, 2026

Efficient Synthesis of All-Carbon Quaternary Centers via the Conjugate Addition of Functionalized Monoorganozinc Bromides
Published on: May 26, 2019
New chiral zinc complexes: synthesis, structure, and induction of axial chirality
Helmut Degenbeck1, Anne-Sophie Felten, Eduardo C Escudero-Adán
1Institute of Chemical Research of Catalonia, Avinguda Països Catalans 16, 43007 Tarragona, Spain.
Abstract:
We describe an efficient methodology for the preparation of new chiral zinc complexes by assembling dynamically racemic biphenol derivatives and chiral 1,2-diamines with suitable zinc(II) precursors. Mononuclear and dinuclear zinc(II) complexes were formed from differently substituted biphenols. The solid-state and solution structural characterization of the resulting compounds allowed us to demonstrate a preferential sense of induced axial chirality for mononuclear complexes, a phenomenon that was not observed for the dinuclear ones.
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