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Updated: May 19, 2026

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection
Published on: December 8, 2014
[A case of pseudomembranous colitis concomitant with toxic megacolon and paralytic ileus]
Takaya Aoki1, Mikinori Kataoka, Yoshiya Sou
1Department of Gastroenterology and Hepatology, Tokyo Medical University Hospital, Japan. aokitakaya0907@yahoo.co.jp
Abstract:
A 60-year-old man was diagnosed as pseudomembranous colitis with chief complaint of fever and abdominal distension after a cerebral operation. It was ineffective although vancomycin hydrochloride (VCM) was given orally. Complications occurred. The patient had toxic megacolon and paralytic ileus. VCM was administrated via an ileus tube. In addition, the bowel was lavaged and VCM was sprayed by colonoscopy. This therapy was very effective. Generally, a patient with pseudomembranous colitis concomitant with toxic megacolon or/and paralytic ileus is considered to have a poor prognosis, however, he completely recovered by a combination of medical treatment.
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