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Updated: Aug 18, 2026

Establishment and Characterization of UTI and CAUTI in a Mouse Model
Published on: June 23, 2015
Review of published studies on single dose therapy of urinary tract infections
1Department of Nephrology, Christchurch Hospital, New Zealand.
Abstract:
The published studies of the use of single dose antimicrobial therapy for the treatment of urinary tract infection have been reviewed. In women and children a single dose of any of several antimicrobial agents was as effective as a course of treatment for uncomplicated urinary tract infections caused by Escherichia coli. Trimethoprim or co-trimoxazole are currently the preferred agents for single dose therapy. Failure of single dose therapy may prove to be a simple guide as to the need for further urinary tract investigation or more intensive therapy. Single dose antimicrobial therapy is now the treatment of choice for uncomplicated urinary tract infections.
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