Related Experiment Video
Updated: May 19, 2026

Visualizing and Tracking Endogenous mRNAs in Live Drosophila melanogaster Egg Chambers
Published on: June 4, 2019
mRNA localization and translational control in Drosophila oogenesis
1Department of Biology, Bellini Life Sciences Building, McGill University, Montréal, Québec H3G 0B1, Canada. paul.lasko@mcgill.ca
Abstract:
Localization of an mRNA species to a particular subcellular region can complement translational control mechanisms to produce a restricted spatial distribution of the protein it encodes. mRNA localization has been studied most in asymmetric cells such as budding yeast, early embryos, and neurons, but the process is likely to be more widespread. This article reviews the current state of knowledge about the mechanisms of mRNA localization and its functions in early embryonic development, focusing on Drosophila where the relevant knowledge is most advanced. Links between mRNA localization and translational control mechanisms also are examined.
Related Concept Videos
Regulated mRNA Transport
Regulation of Expression Occurs at Multiple Steps
Transcription results in the generation of precursor (pre-mRNA) that consists of both exons and introns, which needs further processing before being translated to a...
Regulation of Expression at Multiple Steps
Translational Regulation

