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Implications of new hypertension guidelines in the United States
Monica L Bertoia1, Molly E Waring, Priya S Gupta
1Department of Epidemiology, Warren Alpert Medical School of Brown University, Providence, RI, USA. mbertoia@hsph.harvard.edu
Insights
Millions of Americans have uncontrolled high blood pressure (hypertension), particularly those at high risk for heart disease. Current guidelines vary, highlighting a need for improved hypertension treatment strategies.
Area of Science:
- Cardiology
- Public Health
- Hypertension Management
Background:
- The American Heart Association (AHA) issued hypertension treatment guidelines in 2007 recommending aggressive blood pressure (BP) control (<130/80 mm Hg) for high-risk individuals.
- The 2011 American College of Cardiology Foundation/AHA guidelines suggested a less aggressive BP target (<145/90 mm Hg) for individuals over 80 years old.
Purpose of the Study:
- To estimate the prevalence of uncontrolled BP in adults at increased risk for coronary artery disease (CAD) using both 2007 AHA and 2011 ACCF/AHA hypertension guidelines.
- To compare the estimated burden of hypertension under different guideline recommendations.
Main Methods:
- Cross-sectional analysis of 10,198 adult participants (aged 18-85 years) from the National Health and Nutrition Examination Survey (NHANES) 2005-2008.
- BP data was analyzed using the 2011 ACCF/AHA guidelines (hypertension defined as BP ≥140/90 mm Hg) and the 2007 AHA guidelines.
Main Results:
- Using the 2011 ACCF/AHA guidelines, 72 million Americans (35%) had hypertension.
- Applying the 2007 AHA guidelines identified an additional 7 million adults (5%) with elevated BP requiring treatment, totaling 79 million (40%).
- Individuals at high CAD risk were more likely to be aware of and treated for hypertension but less likely to achieve BP control.
Conclusions:
- A significant portion of the American adult population, especially those at high risk for CAD, has uncontrolled hypertension.
- Discrepancies between guideline recommendations impact the estimated burden of hypertension.
- Enhanced strategies are necessary for effective BP management, particularly in high-risk populations.
Abstract:
The American Heart Association released a scientific statement based on available clinical trials and expert opinion in 2007 for the treatment of hypertension to prevent coronary artery disease. These guidelines recommend more aggressive control of blood pressure (BP <130/80 mm Hg) among those at high risk for coronary artery disease, individuals with diabetes mellitus, chronic kidney disease, coronary artery disease or coronary artery disease risk equivalent, or a 10-year Framingham risk score ≥10%. Based on newer clinical trial data, the 2011 American College of Cardiology Foundation/American Heart Association (AHA) hypertension guidelines for the elderly recommend a less aggressive approach of <145/90 mm Hg in those over the age of 80 years. We estimated the burden of uncontrolled BP among those at an increased risk of coronary artery disease using the both the 2007 AHA and the 2011 American College of Cardiology Foundation/AHA hypertension guidelines. We used a cross-sectional analysis of National Health and Nutrition Examination Survey 2005-2008 participants. Participants were 10198 adults aged 18 to 85 years. Using the 2011 American College of Cardiology Foundation/AHA hypertension guidelines (≥140/90 mm Hg), 72 million Americans (35%) have hypertension. Using the 2007 AHA guidelines, an additional 7 million American adults (5%) have elevated BP requiring treatment, for a total of 79 million adults (40%). Although individuals at a higher risk for coronary artery disease are more likely to be aware of their hypertension and to be taking antihypertension medication, they are less likely to have their BP under control. Additional efforts are needed in the treatment of elevated BP, especially among individuals with an increased risk of coronary artery disease.
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