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[Glioma in the aged (author's transl)]
No to Shinkei = Brain and Nerve
|October 1, 1979
Summary
Malignant gliomas are common in older adults and often present with poor preoperative conditions. Unfavorable outcomes in elderly glioma patients are linked to tumor type and preoperative state, not diagnostic delays.
Area of Science:
- Neurology
- Oncology
- Pathology
Context:
- Glioma is the most common primary brain tumor in the elderly population.
- Malignant gliomas are disproportionately frequent in aged individuals compared to younger demographics.
- Outcomes for glioma surgery and follow-up are generally less favorable in older patients.
Purpose:
- To analyze the characteristics and prognostic factors of glioma in patients over 60 years of age.
- To investigate the relationship between preoperative state, histological type, and prognosis in elderly glioma patients.
- To determine if diagnostic delays or rapid onset influence outcomes in this demographic.
Summary:
- This study reviewed 14 cases of glioma in patients over 60, including glioblastomas and anaplastic astrocytomas.
- A significant majority (71%) presented with poor preoperative states, often due to increased intracranial pressure.
- Unfavorable prognosis was associated with malignant histological types and poor preoperative condition, but not diagnostic delays or rapid progression.
Impact:
- Highlights the aggressive nature of gliomas in the elderly, often presenting late with poor prognostic indicators.
- Suggests that early detection and management strategies may be crucial for improving outcomes in aged glioma patients.
- Provides insights into the specific challenges and factors influencing glioma progression and patient outcomes in an aging population.